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Medical Encyclopedia Adverse Reaction Report Adverse Reaction Chart Drug Label

Welcome to ADRES, the Adverse Drug Reaction Electronic System. This website provides patients, doctors, and other medical professionals with a comprehensive examination of adverse drug reactions (ADRs), side effects, and other safety information for both prescription and over-the-counter medications. Our goal is to allow users of our website make informed decisions when taking (patients) or prescribing (doctors) drugs. We are providing unmatched information and analysis tools.

Check the Fluroquinolones case study

Public Citizen Sues FDA to Force Agency to Act on Petition Seeking Stricter Antibiotic Warnings. Read more...

Safety Alerts

Viagra is investigated for sudden sensorineural hearing loss (SSHL).
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FDA notified healthcare professionals that both conventional and atypical antipsychotics are associated with an increased risk of mortality in elderly patients treated for dementia-related psychosis. Read more...

FDA is investigating a possible association between the use of Singulair and behavior/mood changes, suicidality (suicidal thinking and behavior) and suicide.
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Serious injuries and deaths have been associated with the use of heparin, a blood-thinning drug that contained active pharmaceutical ingredient (API) from China. Read more...
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Several brands of fentanyl transdermal patches are being recalled because they may have defects that could allow the fentanyl gel to leak out of the patch.
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Chantix has been linked to serious neuropsychiatric problems, including changes in behavior, agitation, depressed mood, suicidal ideation and suicide.
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FDA has issued an early communication about serious adverse events, including respiratory failure and death, from Botox and Botox Cosmetic (Botulinum toxin Type A), and Myobloc (Botulinum toxin Type B).
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Women aged 15-44 who used Ortho Evra Contraceptive Transdermal Birth Control Patch are at higher risk of developing venous thromboembolism than women using birth control pills.
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Read more...


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ADRES is based on the FDA's Adverse Event Reporting System (AERS), and is designed to make post-marketing safety data and regulatory information easy to use and interpret so we, consumers and doctors are well informed before taking medication. For researchers, this database can be an invaluable resource for examination of adverse event reports.

According to the FDA, Adverse Drug Reactions cause more than 106,000 deaths annually making them the 4th leading cause of death—ahead of pulmonary disease, diabetes, AIDS, pneumonia, accidents, and automobile deaths.

Click here for top 20 drugs with adverse drug reactions

What you need to know about ADRs: (Source: FDA)

  • Costs $136 BILLION yearly
  • Greater than total costs of cardiovascular or diabetic care
  • ADRs cause 1 out of 5 injuries or deaths per year to hospitalized patients
  • Two-thirds of patient visits result in a prescription
  • 2.8 BILLION Outpatient prescriptions (10 per person in the United States) filled in 2000
  • Adverse Drug Reactions increase exponentially with 4 or more medications

A case study of the risk of Tendon Rupture with Fluoroquinolones antibiotics

A case study of the increased cardiovascular risk with Cox-2 Inhibitors



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Is it an adverse 'Event' (AE) or an adverse drug 'Reaction' (ADR)?

There is some debate and inconsistencies regarding the definition of Adverse Drug Reactions. If you call it an adverse event, you may not have a culprit drug in mind, whereas calling it an adverse drug reaction is already linking it to a suspected drug. Regardless of whether or not there is a suspected drug, an AE or an ADR is commonly defined as any adverse change in health or un-desired "side-effect" that occurs in a person while on a medical treatment (for example, drug or device) or within a pre-specified period after treatment is complete. Not every adverse event is causally related to the treatment or test being studied. However, regardless of causality, people who experienced adverse reactions, or their doctors, are encouraged to report these events to the FDA or the relevant regulatory authority in the country where the drug or device is registered.

Check adverse drug reaction reports of prescription drugs such as Celebrex, Viagra (sildenafil), Cialis, Levitra, Vioxx, Accutane, Prozac, Lexapro, Paxil, Plavix, and others Check adverse drug reaction reports of commonly used over-the-counter drugs such as aspirin, Ibuprofen, acetaminophen, Tylenol, and others

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